Oxalic Acid → HCID 69743753, compound

Participants

Reaction Steps

The product from step (e) (140 mg, 0.39 mmol) was dissolved in 4M hydrochloric acid in dioxan and stirred at room temperature for 2 h. The solvent was removed in vacuo and the residue partitioned between ethyl acetate and aqueous saturated sodium bicarbonate solution. The organic layer was separated and washed with water (2×20 ml), dried (magnesium sulphate) and evaporated in vacuo. The residue was dissolved in ethyl acetate (5 ml) and treated with one equivalent of oxalic acid. The precipitated solid was filtered off and dried to give the title compound (30 mg, 22%).

Provenance & Evidence