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HRID2183872

反应详情

EQUATION

反应方程式

HRID 2183872 的结构方程式

REACTANTS

反应物

2
反应SMILES：CC1(C)OB(c2ccc(F)c(-c3ccccc3C#N)c2)OC1(C)C
HCID11771647

2′-Fluoro-5′-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)[1,1′-biphenyl]-2-carbonitrile

C19H19BFNO2

反应SMILES：CC(C)(C)c1ccn2c(Br)cnc2n1
HCID18001287

未命名化合物

PRODUCTS

产物

1
反应SMILES：CC(C)(C)c1ccn2c(-c3ccc(F)c(-c4ccccc4C#N)c3)cnc2n1
HCID10109710

未命名化合物

PROCEDURE

实验过程

3-Bromo-7-tert-butylimidazo[1,2-α]pyrimidine was coupled with 2′-fluoro-5′-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)biphenyl-2-carbonitrile as described in Example 1 to give 2′-fluoro-5′-(7-tert-butylimidazo[1,2-α]pyrimidin-3-yl)biphenyl-2-carbonitrile as an off-white powder: δH (360 MHz, CDCl3) 1.43 (9H, s), 7.05 (1H, d, J 7), 7.37-7.73 (6H, m), 7.81 (1H, s), 7.85 (1H, dd, J 8 and 1), 8.75 (1H, d, J 7); m/z (ES+) 371 (M++H).