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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2183941Generated: October 31, 2026

Trimethyl borate → 2-Fluoro-3-(pyridin-3-yl)phenylboronic acid

https://huagongshe.com/reaction/2183941

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrimethyl borateHCID 8470—
Reactant3-(2-Fluorophenyl)pyridineHCID 13270645—
Product2-Fluoro-3-(pyridin-3-yl)phenylboronic acidHCID 22285316—

Reaction Steps

3-(2-Fluorophenyl)pyridine was lithiated and reacted with trimethyl borate as described in Example 31 to give 2-fluoro-3-(pyridin-3-yl)benzeneboronic acid as a white solid: m/z (ES+) 218 (M++H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06900215B2
Source datasetuspto-grants-2005_05
ORD IDord-1e80b2503fee485a99dbf375bc844f90
Source noteuspto-grants-2005_05