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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2184029Generated: October 31, 2026

Benzonitrile, 4-bromo- → HCID 22285304, compound

https://huagongshe.com/reaction/2184029

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzonitrile, 4-bromo-HCID 12162—
Reactant2-Fluoro-5-nitrophenylboronic acid, pinacol esterHCID 3833297—
ProductHCID 22285304HCID 22285304—

Reaction Steps

4-Bromobenzonitrile and 2-(2-fluoro-5-nitrophenyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane were coupled using the procedure described in Example 1 to afford 2′-fluoro-5′-nitrobiphenyl-4-carbonitrile as a brown solid: δH (400 MHz, CDCl3) 7.37 (1H, dd, J 9 and 9), 7.70 (2H, dd, J 8 and 1), 7.80 (1H, dd, J 8 and 1), 8.29-8.33 (1H, m), 8.37-8.40 (1H, m).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06900215B2
Source datasetuspto-grants-2005_05
ORD IDord-79fa5924e5fa413896f48f2f4556145b
Source noteuspto-grants-2005_05