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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2184031Generated: October 31, 2026

2-Bromo-6-nitrotoluene → HCID 22473548, compound

https://huagongshe.com/reaction/2184031

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Bromo-6-nitrotolueneHCID 123537—
Reactant5-Fluoro-2-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrileHCID 22180790—
ProductHCID 22473548HCID 22473548—

Reaction Steps

2-Bromo-6-nitrotoluene and 5-fluoro-2-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)benzonitrile were coupled using the procedure described in Example 1 to afford crude 4-fluoro-2′-methyl-3′-nitrobiphenyl-2-carbonitrile as a black solid: δH (360 MHz, CDCl3) 2.32 (3H, s), 7.34-7.46 (5H, m), 7.95 (1H, m).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06900215B2
Source datasetuspto-grants-2005_05
ORD IDord-69a04841e22347f2bc238744a70bf68e
Source noteuspto-grants-2005_05