3-Bromo-7-(trifluoromethyl)imidazo[1,2-a]pyrimidine → HCID 9924315, compound

Participants

Reaction Steps

3-Bromo-7-trifluoromethylimidazo[1,2-α]pyrimidine was coupled to 1-[5-(5,5-dimethyl-[1,3,2]dioxaborinan-2-yl)-2-fluorophenyl]-1H-pyrrole by the method of Example 65 to furnish 3-[4-fluoro-3-(pyrrol-1-yl)phenyl]-7-trifluoromethylimidazo[1,2-α]pyrimidine: δH (400 MHz, DMSO) 9.37 (1H, d, J 7), 8.33 (1H, s), 7.97 (1H, d, J 8 and 2), 7.75-7.62 (2H, m), 7.52 (1H, d, J 7), 7.30 (2H, q, J 2), 6.32 (2H, t, J 2); m/z (ES+) 347 (M+H+).

Provenance & Evidence