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HRID2184065

反应详情

EQUATION

反应方程式

HRID 2184065 的结构方程式

REACTANTS

反应物

2
结构：CC1(C)OB(c2cc([N+](=O)[O-])ccc2F)OC1(C)C
HCID3833297

2-(2-Fluoro-5-nitrophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

C12H15BFNO4

结构：O=S(=O)(Oc1cncc(F)c1)C(F)(F)F
HCID11413882

Methanesulfonic acid, trifluoro-, 5-fluoro-3-pyridinyl ester

C6H3F4NO3S

PRODUCTS

生成物

1
结构：O=[N+]([O-])c1ccc(F)c(-c2cncc(F)c2)c1
HCID22473544

未命名化合物

PROCEDURE

实验过程

Trifluoromethanesulfonic acid 5-fluoropyridin-3-yl ester was coupled with 2-(2-fluoro-5-nitrophenyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane as described in Example 1 to give 3-fluoro-5-(2-fluoro-5-nitrophenyl)pyridine as a white solid: δH (360 MHz, CDCl3) 7.39 (1H, t, J 9), 7.65 (1H, m), 8.31-8.36 (1H, m), 8.42 (1H, dd, J 7 and 3), 8.58 (1H, d, J 3), 8.67 (1H, d, J 1).