Fluorobenzene → Bis(4-fluorophenyl)methylene chloride

HRID 2184109Notes

Reaction equation

HRID 2184109 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](F)(F)F)=[CH:4][CH:3]=1.[Al+3].[Cl-:13].[Cl-:14].[Cl-].[F:16][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>>[F:16][C:17]1[CH:22]=[CH:21][C:20]([C:8]([C:5]2[CH:4]=[CH:3][C:2]([F:1])=[CH:7][CH:6]=2)([Cl:14])[Cl:13])=[CH:19][CH:18]=1

Participants

4

Reactant 3

HCID 10008FluorobenzeneHCID 67873Benzene, 1-fluoro-4-(trifluoromethyl)-HCID 6451240Aluminum(III) Chloride

Product 1

HCID 12714043Bis(4-fluorophenyl)methylene chloride

Procedure

From 4-fluorobenzotrifluoride (164 mg, 1 mmol), AlCl3 (400 mg, 3 mmol) and fluorobenzene (96 mg, 1 mmol), light yellow oil (377 mg, 138% crude).

Sources & evidence

ORD record
ord-9921fdf7f1bd4e13b06771c49868c68a
Source dataset
uspto-grants-2005_05
Patent number
US06900227B2

Reaction notes

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