HuagongsheHuagongshe Chemistry Print Report · For research reference only
Azobisisobutyronitrile → 4-(Bromomethyl)-2-methoxybenzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Azobisisobutyronitrile | HCID 6547 | — |
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Reactant | 2-Methoxy-4-methylbenzonitrile | HCID 12495373 | — |
| Solvent | 1,2-Dichloroethane | HCID 11 | — |
| Product | 4-(Bromomethyl)-2-methoxybenzonitrile | HCID 21985007 | 35.3% |
Reaction Steps
4.6 g (31.3 mmol) of 4-methyl-2-methoxybenzonitrile were brominated with 34.7 mmol of N-bromosuccinimide in the presence of catalytic amounts of azobisisobutyronitrile in 60 ml of 1,2-dichloroethane under reflux. 2.5 g of the product were obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06900319B2 |
| Source dataset | uspto-grants-2005_05 |
| ORD ID | ord-f2c55738ca0045f9a91f7f60d454fdd5 |
| Source note | uspto-grants-2005_05 |