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HRID2184254

反应详情

EQUATION

反应方程式

HRID 2184254 的结构方程式

REACTANTS

反应物

2
反应SMILES：C[C@@H]1CN(C(=O)c2ccccc2)CCN1C(=O)C(=O)c1c[nH]c2ncccc12
HCID5495793

1-(4-Benzoyl-2-methylpiperazin-1-yl)-2-(1H-pyrrolo[2,3-b]pyridin-3-yl)ethane-1,2-dione

C21H20N4O3

反应SMILES：COc1cnc(Cl)c2[nH]cc(C(=O)C(=O)[O-])c12.[K+]
HCID22893812

未命名化合物

PRODUCTS

产物

1
反应SMILES：COc1cnc(Cl)c2[nH]cc(C(=O)C(=O)N3CCN(C(=O)c4ccccc4)CC3)c12
HCID5495838

未命名化合物

PROCEDURE

实验过程

Compound 5an, N-(benzoyl)-N′-[(7-chloro-4-methoxy-6-azaindol-3-yl)-oxoacetyl]-piperazine was prepared by the same method which was used to prepare compound 5a except that Potassium (7-chloro-4-methoxy-6-azaindol-3-yl)-oxoacetate was employed as the starting material to give a white solid. The compound was purified by silica gel chromatography using EtOAc as the eluting solvent. MS m/z: (M+H)+ calcd for C21H20ClN4O4: 427.12; found 427.12. HPLC retention time: 1.28 minutes (column A).

WORKUP

后处理

  1. customto give a white solid
  2. customThe compound was purified by silica gel chromatography