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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2184256Generated: October 31, 2026

Piperazine, 4-benzoyl-1-(1,2-dioxo-2-(1H-pyrrolo(2,3-b)pyridin-3-yl)ethyl)-2-methyl-, (2R)- → n-(Benzoyl)-3-methyl-n'-[(4,7-dimethoxy-6-azaindol-3-yl)-oxoacetyl]piperazine

https://huagongshe.com/reaction/2184256

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPiperazine, 4-benzoyl-1-(1,2-dioxo-2-(1H-pyrrolo(2,3-b)pyridin-3-yl)ethyl)-2-methyl-, (2R)-HCID 5495793—
ReactantPotassium (4,7-dimethoxy-6-azaindol-3-yl)-oxoacetateHCID 22893810—
Productn-(Benzoyl)-3-methyl-n'-[(4,7-dimethoxy-6-azaindol-3-yl)-oxoacetyl]piperazineHCID 22476268—

Reaction Steps

Compound 5ap, ®-N-(benzoyl)-3-methyl-N′-[(4,7-dimethoxy-6-azaindol-3-yl)-oxoacetyl]-piperazine (white solid) was prepared using the same method used to prepare compound 5a except that Potassium (4,7-dimethoxy-6-azaindol-3-yl)-oxoacetate was used as the starting material. MS m/z: (M+H)+ calcd for C23H25N4O5: 437.18; found 437.24. HPLC retention time: 1.37 minutes (column B).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06900323B2
Source datasetuspto-grants-2005_05
ORD IDord-9be079a7f829472496710911baf12bbe
Source noteuspto-grants-2005_05