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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2184367Generated: October 29, 2026

Methylamine → 3-{4-[(4-Fluorophenyl)methoxy]phenyl}-N-methylprop-2-enamide

https://huagongshe.com/reaction/2184367

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethylamineHCID 6329—
Reactant3-[4-[(4-fluorophenyl)methoxy]phenyl]prop-2-enoic AcidHCID 805382—
Product3-{4-[(4-Fluorophenyl)methoxy]phenyl}-N-methylprop-2-enamideHCID 6866909621%

Reaction Steps

The title compound is prepared in analogy to example 12 b) from 3-[4-(4-fluoro-benzyloxy)-phenyl]-acrylic acid and methylamine. Yield=21%. Colorless solid. MS: m/e=286.0 (M++H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06900354B2
Source datasetuspto-grants-2005_05
ORD IDord-cb35523b78bd4be2ad4c83d9613ee1a8
Source noteuspto-grants-2005_05