2-Propanesulfonyl chloride → HCID 10225755, compound
Reaction equation
[CH3:1][CH:2]([S:4](Cl)(=[O:6])=[O:5])[CH3:3].[NH2:8][CH2:9][CH2:10][O:11][C:12]1[CH:17]=[CH:16][C:15]([C:18]2([OH:30])[CH2:22][CH2:21][CH2:20][CH:19]2[NH:23][S:24]([CH:27]([CH3:29])[CH3:28])(=[O:26])=[O:25])=[CH:14][CH:13]=1>>[OH:30][C:18]1([C:15]2[CH:16]=[CH:17][C:12]([O:11][CH2:10][CH2:9][NH:8][S:4]([CH:2]([CH3:3])[CH3:1])(=[O:6])=[O:5])=[CH:13][CH:14]=2)[CH2:22][CH2:21][CH2:20][CH:19]1[NH:23][S:24]([CH:27]([CH3:28])[CH3:29])(=[O:26])=[O:25]Participants
3
Procedure
The title compound is prepared in a manner analogous to the procedure set forth in example 51 from 2-propanesulfonyl chloride and {2-[4-(2-aminoethoxy)phenyl]-2-hydroxycyclopentyl}[(methylethyl)sulfonyl]amine.
Sources & evidence
- ORD record
- ord-962873a313ea4cdbac2e3f9ee34e7b3c
- Source dataset
- uspto-grants-2005_05
- Patent number
- US06900353B2
Reaction notes
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