HCID 12985406, compound → HCID 11265620, compound

Participants

Reaction Steps

The product of Step 3 (73 mg, 0.20 mmole) was dissolved in tetrahydrofuran (3 mL) and 10% palladium on charcoal (65 mg) was added. The mixture was flushed thrice with nitrogen, thrice with hydrogen, and then stirred under hydrogen for 45 min. The mixture was filtered through Celite, the Celite was rinsed with ethyl acetate (10 mL), and the combined filtrates were evaporated to give 3-[2-tetrahydropyranyloxy]4-bromobutanoic acid as a colourless oil, 54 mg (98%). IR (neat): 1715 cm−1. Mass spectrum (CI, m/z): 267, 269 (M+1, M+3).

Provenance & Evidence