4-(1-Acetylpiperidin-4-yl)furo[3,2-c]pyridine → 4-(4-Piperidinyl)furo[3,2-c]pyridine

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Reaction Steps

A solution of 2.7 g of the product obtained in Step D in 80 ml of HCl (4N) is heated at 100° C. for 12 hours and then cooled, washed with ether, and rendered basic to a pH of 10 by the addition of an aqueous sodium hydroxide solution. After extraction with dichloromethane, the organic phase is dried, filtered and then evaporated to dryness enabling the expected product to be obtained.

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