1-Bromopropane → HCID 22458140, compound

Participants

Reaction Steps

A mixture of 0.17 g of the compound 49A of example 49, 0.14 g of anhydrous potassium carbonate, 0.2 mL of 1-bromopropane and 3 ml, of DMF was stirred at 60° C. under nitrogen atmosphere for 6 h. The cooled mixture was filtered, poured into 50 mL of H2O and extracted with EtOAc. The organic layer, dried on anhydrous Na2SO4, was evaporated to dryness to give 0.10 g (62%) of the title compound.

Provenance & Evidence