反应详情

温度

120 °C

The title compound was obtained following the procedure described for example 54, but using 1-(2-trifluoromethoxyphenyl)piperazine in place of 1-(4-nitro-2-methoxyphenyl)piperazine. The reaction mixture was heated at 120° C. for 8 h. The residue obtained by usual work-up and extraction with Et2O was purified by flash chromatography (petroleum ether-EtOAc gradient from 90:10 to 80:20) to afford the title compound. Yield: 41%.

1. customwas purified by flash chromatography (petroleum ether-EtOAc gradient from 90:10 to 80:20)