HRID2184850

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：COc1ccccc1N1CCN(CCN(C(=O)C2CCCCC2)c2ccccc2N)CC1

HCID18782313

未命名化合物

结构：COc1cc(N)ccc1N1CCN(CCN(C(=O)C2CCCCC2)c2ccccc2C#N)CC1

HCID22458092

未命名化合物

PRODUCTS

生成物

结构：COc1cc(NC(C)=O)ccc1N1CCN(CCN(C(=O)C2CCCCC2)c2ccccc2C#N)CC1

HCID22458144

未命名化合物

CONDITIONS

反应条件

温度: 22.5 °C

PROCEDURE

实验过程

The title compound was synthesized according to the procedure reported in example 28 but substituting the compound of example 79 for the compound of example 27 and stirring at 20-25° C. for 17 h. The usual work-up afforded the title compound. Yield: 49%.

WORKUP

后处理

customThe title compound was synthesized

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-eba033b531a64b1ab9abd7f83f9783b8
来源数据集: uspto-grants-2002_06
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06399614B1
来源说明: uspto-grants-2002_06

反应 SMILES

[C:1]([C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[N:9]([C:27]([CH:29]1[CH2:34][CH2:33][CH2:32][CH2:31][CH2:30]1)=[O:28])[CH2:10][CH2:11][N:12]1[CH2:17][CH2:16][N:15]([C:18]2[CH:23]=[CH:22][C:21]([NH2:24])=[CH:20][C:19]=2[O:25][CH3:26])[CH2:14][CH2:13]1)#[N:2].NC1C=CC=CC=1N(C(C1CCCCC1)=O)CCN1CCN([C:51]2C=CC=C[C:52]=2[O:57]C)CC1>>[C:1]([C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[N:9]([C:27]([CH:29]1[CH2:34][CH2:33][CH2:32][CH2:31][CH2:30]1)=[O:28])[CH2:10][CH2:11][N:12]1[CH2:13][CH2:14][N:15]([C:18]2[CH:23]=[CH:22][C:21]([NH:24][C:52](=[O:57])[CH3:51])=[CH:20][C:19]=2[O:25][CH3:26])[CH2:16][CH2:17]1)#[N:2]