2'-Aminoacetophenone → N-(2-Acetylphenyl)cyclohexanecarboxamide

HRID 2184851Notes

Reaction equation

HRID 2184851 reaction equation
FC(F)(F)C1C=CC=CC=1N[C:10]([CH:12]1[CH2:17][CH2:16][CH2:15][CH2:14][CH2:13]1)=[O:11].[C:20]([C:23]1[CH:29]=[CH:28][CH:27]=[CH:26][C:24]=1[NH2:25])(=[O:22])[CH3:21]>>[C:20]([C:23]1[CH:29]=[CH:28][CH:27]=[CH:26][C:24]=1[NH:25][C:10]([CH:12]1[CH2:17][CH2:16][CH2:15][CH2:14][CH2:13]1)=[O:11])(=[O:22])[CH3:21]

Participants

3

Reactant 2

HCID 110862'-AminoacetophenoneHCID 1367212N-[2-(trifluoromethyl)phenyl]cyclohexanecarboxamide

Product 1

HCID 584888N-(2-Acetylphenyl)cyclohexanecarboxamideYield 90%

Procedure

This compound was prepared following the procedure described for compound 26A of example 26, except that 2-acetylaniline was used in place of 2-trifluoromethylaniline. Yield: 90%.

Workup

  1. customThis compound was prepared

Sources & evidence

ORD record
ord-f7975d14192442a39efe95a2f63c63fa
Source dataset
uspto-grants-2002_06
Patent number
US06399614B1

Reaction notes

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