2-(Trifluoromethoxy)aniline → N-(2-trifluoromethoxyphenyl)cyclohexanecarboxamide
Reaction equation
FC(F)(F)[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[NH:9][C:10]([CH:12]1[CH2:17][CH2:16][CH2:15][CH2:14][CH2:13]1)=[O:11].[F:20][C:21]([F:31])([F:30])[O:22]C1C=CC=CC=1N>>[F:20][C:21]([F:31])([F:30])[O:22][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[NH:9][C:10]([CH:12]1[CH2:13][CH2:14][CH2:15][CH2:16][CH2:17]1)=[O:11]Participants
3
Procedure
This compound was prepared following the procedure described for compound 26A of example 26, except that 2-trifluoromethoxyaniline was used in place of 2-trifluoromethylaniline. Yield: 100%.
Workup
- customThis compound was prepared
Sources & evidence
- ORD record
- ord-cf466f14791f4f9fb24471eb3ee69d1a
- Source dataset
- uspto-grants-2002_06
- Patent number
- US06399614B1
Reaction notes
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