HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,4-Dichloroaniline → N-(3,4-dichlorophenyl)alanine Methyl Ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,4-Dichloroaniline | HCID 7257 | — |
| Reactant | Methyl pyruvate | HCID 11748 | — |
| Product | N-(3,4-dichlorophenyl)alanine Methyl Ester | HCID 54289412 | — |
Reaction Steps
Following General Procedure A above and using 3,4-dichloroaniline (Aldrich) and methyl pyruvate (Aldrich), the title compound was prepared as an oil. The reaction was monitored by tlc on silica gel (Rf=0.55 in 25% EtOAc/hexanes) and purification was by flash chromatography (silica gel using 25% EtOAc/hexanes as the eluant).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06399628B1 |
| Source dataset | uspto-grants-2002_06 |
| ORD ID | ord-1b8e644feed44ca1894accfae352a9de |
| Source note | uspto-grants-2002_06 |