Cyclohexanemethanol → N-(3,4-dichlorophenyl)alanine cyclohexylmethyl Ester

HRID 2184871Notes

Reaction equation

HRID 2184871 reaction equation
[CH3:1][O:2][C:3](=[O:15])[C@H:4]([CH3:14])[NH:5][C:6]1[CH:11]=[CH:10][C:9]([Cl:12])=[C:8]([Cl:13])[CH:7]=1.[CH:16]1(CO)[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17]1>>[CH:16]1([CH2:1][O:2][C:3](=[O:15])[C@H:4]([CH3:14])[NH:5][C:6]2[CH:11]=[CH:10][C:9]([Cl:12])=[C:8]([Cl:13])[CH:7]=2)[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17]1

Participants

3

Reactant 2

HCID 7507CyclohexanemethanolHCID 54289412N-(3,4-dichlorophenyl)alanine Methyl Ester

Product 1

HCID 54064964N-(3,4-dichlorophenyl)alanine cyclohexylmethyl Ester

Procedure

Following transesterification General Procedure B above and using N-(3,4-dichlorophenyl)alanine methyl ester (from Example 9 above) and cyclohexylmethanol (Aldrich), the title compound was prepared.

Sources & evidence

ORD record
ord-3ba98d203c434b4e8f1e9044c6da660f
Source dataset
uspto-grants-2002_06
Patent number
US06399628B1

Reaction notes

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