HCID 44284734, compound → HCID 22458385, compound

Participants

Reaction Steps

To a solution of 3-((1E)-1-(methoxymethyl)-2-{N-[4-(2-sulfamoylphenyl)phenyl]carbamoyl}vinyl)-benzenecarboxamidine (5 mg, 0.01 mmol) in 4 ml methanol was added 10% Pd on carbon (1 mg). Mixture was treated with hydrogen at 1 atmosphere under balloon for 1 hr. Reaction was filtered through a pad of Celite, concentrated and lyophilized to give 3-(1-(methoxymethyl)-2-{N-[4-(2-sulfamoylphenyl)phenyl]carbamoyl}-ethyl)benzenecarboxamidine (5 mg, 100%) as a fluffy white powder. ES-MS (M+H+): 467.15

Provenance & Evidence