9H-xanthene-9-carbonyl chloride → 9H-Xanthene-9-carboxylic acid (2-cyclopropylmethyl-2H-tetrazol-5-yl)-amide

HRID 2184968Notes

Reaction equation

HRID 2184968 reaction equation
[NH2:1][C:2]1[N:3]=[N:4][N:5]([CH2:7][CH:8]2[CH2:10][CH2:9]2)[N:6]=1.[CH:11]1[C:24]2[CH:23]([C:25](Cl)=[O:26])[C:22]3[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=3)[O:16][C:15]=2[CH:14]=[CH:13][CH:12]=1>>[CH:8]1([CH2:7][N:5]2[N:4]=[N:3][C:2]([NH:1][C:25]([CH:23]3[C:24]4[CH:11]=[CH:12][CH:13]=[CH:14][C:15]=4[O:16][C:17]4[C:22]3=[CH:21][CH:20]=[CH:19][CH:18]=4)=[O:26])=[N:6]2)[CH2:10][CH2:9]1

Participants

3

Reactant 2

HCID 27608929H-xanthene-9-carbonyl chlorideHCID 22459177HCID 22459177, compound

Product 1

HCID 99243779H-Xanthene-9-carboxylic acid (2-cyclopropylmethyl-2H-tetrazol-5-yl)-amide

Procedure

The title compound, white solid, m.p. 222-224° C. and MS: (neg. ions): m/e=346.2 (M+−H) was prepared in accordance with the general method of example 1 from 5-amino-2-cyclopropylmethyl-2H-tetrazole and 9H-xanthene-9-carbonyl chloride.

Sources & evidence

ORD record
ord-b8568ca824d34233a5d7e3424ba39652
Source dataset
uspto-grants-2002_06
Patent number
US06399641B1

Reaction notes

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