Hydrochloric Acid → HCID 22458926, compound

Participants

Reaction Steps

To a solution of 4-phenoxy-2-propylphenol (PCT Application WO97/281 15) in DMF was added potassium carbonate and allyl bromide. The reaction was stirred for 5 h at 50C, and after cooling was neutralized with 1N HCl and extracted with ethyl acetate. The organic extract was washed with brine, dried over magnessium sulphate, filtered and concentrated to afford an oil which was chromatographed on silica gel (15% ethyl acetate:hexanes) to afford 2-propyl-4-phenoxyphenyl allyl ether.

Provenance & Evidence