Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ziprasidone | HCID 60854 | — |
| Reactant | L-Tartaric acid | HCID 444305 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 86583591 | HCID 86583591 | — |
Reaction Steps
1 g of ziprasidone free base was added to 60 mL of water and the resulting slurry was heated to 50° C. for 3 hours with stirring. 900 mg of L-tartaric acid was added. Heating at 50° C. and stirring were continued for 6 more hours, and then the mixture was stirred at 40° C. overnight. The solution was then allowed to cool and the salt harvested as in Example 5.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06399777B2 |
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| Source dataset | uspto-grants-2002_06 |
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| ORD ID | ord-4dba761eda954b5081b730e117e52487 |
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| Source note | uspto-grants-2002_06 |
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