4,4-Dicyano-3-methyl-3-butenal dimethyl acetal → 4-Methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile

HRID 2185123Notes

Reaction equation

HRID 2185123 reaction equation
CO[CH:3](OC)[CH2:4][C:5]([CH3:11])=[C:6]([C:9]#[N:10])[C:7]#[N:8].C(C(C#N)=C(C)C=C[O:20]C)#N>O>[C:7]([C:6]1[C:9](=[O:20])[NH:10][CH:3]=[CH:4][C:5]=1[CH3:11])#[N:8]

Participants

4

Reactant 2

HCID 99423034,4-Dicyano-3-methyl-3-butenal dimethyl acetalHCID 725894471,1-Dicyano-4-methoxy-2-methyl-1,3-butadiene

Product 1

HCID 106067824-Methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

treating the mixture of 4,4-dicyano-3-methyl-3-butenal dimethyl acetal and 1,1-dicyano-4-methoxy-2-methyl-1,3-butadiene so produced with a strong acid and water, to yield 3-cyano-4-methyl-2-pyridone

Workup

  1. additiontreating

Sources & evidence

ORD record
ord-49f676bd5f904e119001b3a83460dd71
Source dataset
uspto-grants-2002_06
Patent number
US06399781B1

Reaction notes

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