HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethyl Succinate → HCID 22460019, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethyl Succinate | HCID 7820 | — |
| Reactant | 2,4-Dimethoxybenzaldehyde | HCID 69175 | — |
| Reactant | Sodium Acetate | HCID 517045 | — |
| Reactant | Potassium tert-butoxide | HCID 23665647 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Acetic Anhydride | HCID 7918 | — |
| Product | HCID 22460019 | HCID 22460019 | — |
| Product | HCID 22460020 | HCID 22460020 | — |
Reaction Steps
5,7-dimethoxy-3-methoxycarbonyl-1-acetoxynaphthalene is synthesized according to the procedure described in Org. React. 1951, 6, 1; by the reaction of 2,4-dimethoxybenzaldehyde and dimethyl succinate in the presence of potassium tert-butoxide followed by a cyclization in acetic anhydride in the presence of sodium acetate. 5,7-dimethoxy-3-methoxycarbonyl-1-naphthol is then obtained after deacetylation of the preceding product in HCl(2N)/methanol under reflux for 3 hours.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06399791B1 |
| Source dataset | uspto-grants-2002_06 |
| ORD ID | ord-5f837e0df9354e659b5fe55764f29cf3 |
| Source note | uspto-grants-2002_06 |