1-Pyrrolidineethanamine → HCID 3357107, compound

HRID 2185176Notes

Reaction equation

[C:1]([NH:4][C:5]1[CH:10]=[CH:9][C:8]([S:11](Cl)(=[O:13])=[O:12])=[CH:7][CH:6]=1)(=[O:3])[CH3:2].[N:15]1([CH2:20][CH2:21][NH2:22])[CH2:19][CH2:18][CH2:17][CH2:16]1>>[N:15]1([CH2:20][CH2:21][NH:22][S:11]([C:8]2[CH:9]=[CH:10][C:5]([NH:4][C:1](=[O:3])[CH3:2])=[CH:6][CH:7]=2)(=[O:13])=[O:12])[CH2:19][CH2:18][CH2:17][CH2:16]1

Participants

Reactant 2

HCID 13441-Pyrrolidineethanamine

HCID 8481N-Acetylsulfanilyl chloride

Product 1

HCID 3357107HCID 3357107, compound

Procedure

Starting from 4-acetylaminobenzenesulfonyl chloride and 2-pyrrolidin-1-ylethylamine, the title compound is prepared analogously to the method described in Example 10, intermediate 2. The crude product thus obtained can be used for further reaction without further purification. (MS-ES+: 312.1; LCMS Rt=1.957 min)

Sources & evidence

ORD record: ord-aa47161b28904df4aa7b8f5458075e7b
Source dataset: uspto-grants-2002_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06399824B1

Reaction notes

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