HCID 59586684, compound → HCID 59586681, compound

Participants

Reaction Steps

130 mg (0.45 mmol) of the product from example 52A are initially charged in 4 ml of THF. To this are added 50 mg of 10% palladium on activated carbon, and hydrogenation is effected at standard pressure in a hydrogen atmosphere for 1 h. The reaction solution is then filtered through Celite which is rinsed with ethyl acetate. The mixture is concentrated under reduced pressure to obtain 115 mg (99% of theory) of the crystalline title compound.

Provenance & Evidence