Methyl iodide → HCID 59586699, compound

HRID 218523Notes

Reaction equation

HRID 218523 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[C:7]([N+:9]([O-:11])=[O:10])[CH:6]=[CH:5][C:4]=1[C:12]1[C:13](=[O:18])[NH:14][CH:15]=[CH:16][CH:17]=1.[CH3:19]I>>[CH3:1][O:2][C:3]1[CH:8]=[C:7]([N+:9]([O-:11])=[O:10])[CH:6]=[CH:5][C:4]=1[C:12]1[C:13](=[O:18])[N:14]([CH3:19])[CH:15]=[CH:16][CH:17]=1

Participants

3

Reactant 2

HCID 6328Methyl iodideHCID 595867673-(2-Methoxy-4-nitrophenyl)pyridin-2(1H)-one

Product 1

HCID 59586699HCID 59586699, compound

Procedure

350 mg (1.42 mmol) of the product from example 55A are alkylated analogously to example 56A with 242 mg (1.71 mmol) of methyl iodide. This affords 347 mg (88% of theory) of the title compound.

Sources & evidence

ORD record
ord-d2b9269cf6244925a2d7d8772229422f
Source dataset
uspto-grants-2012_06
Patent number
US08198267B2

Reaction notes

Loading…