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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 218553Generated: October 31, 2026

2,4-Dimethoxyaniline → 4-benzyloxy-N-(2,4-dimethoxyphenyl)indan-1-carboxamide

https://huagongshe.com/reaction/218553

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-DimethoxyanilineHCID 17652—
Reactant4-Benzyloxyindan-1-carboxylic acidHCID 17854458—
Product4-benzyloxy-N-(2,4-dimethoxyphenyl)indan-1-carboxamideHCID 1785416479.8%

Reaction Steps

By the reaction and treatment in the same manner as in Preparation Example 18 using 4-benzyloxyindan-1-carboxylic acid (0.8 g) and 2,4-dimethoxyaniline (0.5 g) as starting materials, 4-benzyloxy-N-(2,4-dimethoxyphenyl) indan-1-carboxamide (0.96 g) was obtained. melting point: 129.7° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08198454B2
Source datasetuspto-grants-2012_06
ORD IDord-245587c0c22d4378ad2b59d5c23ccb7e
Source noteuspto-grants-2012_06