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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2185549Generated: October 31, 2026

HCID 22458231, compound → HCID 21341103, compound

https://huagongshe.com/reaction/2185549

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 22458231HCID 22458231—
Reactantalpha-(R)-(3-(R)-formyl-4-(S)-phenylpyrrolidin-1-yl)-cyclohexaneacetic acid 4-methoxybenzyl esterHCID 53654320—
ProductHCID 21341103HCID 2134110363.4%

Reaction Steps

The title compound was prepared from 4-(N-(N-(4-nitrobenzyl)carbamoyl)-N-(prop-1-yl)amino)-piperidine trifluoroacetate (21 mg, 0.048 mmol, from Step A) and 2-(R)-(3-(R)-formyl-4-(S)-phenyl-pyrrolidin-1-yl)-2-(cyclohexyl)acetic acid, (4-methoxy)benzyl ester (14 mg, 0.028 mmol, Aldehyde 5) according to the method described in Example 1, Step C to give 11 mg (63%) of the title compound. ESI-MS: 620.4 (M+H); HPLC A: 2.33 min.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06399619B1
Source datasetuspto-grants-2002_06
ORD IDord-d8848103c20e41ba8f120be94490a1c6
Source noteuspto-grants-2002_06