HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 22458245, compound → HCID 21341098, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 22458245 | HCID 22458245 | — |
| Reactant | HCID 57255963 | HCID 57255963 | — |
| Product | HCID 21341098 | HCID 21341098 | 38% |
Reaction Steps
The title compound was prepared from 4-((N-(4-(trifluoromethyl)benzyl)carbamoyl)methyl)-piperidine hydrochloride (34 mg, 0.1 mmol, from Step A) and 2-(R)-(3-(R)-formyl-4-(S)-(3-fluorophenyl)-pyrrolidin-1-yl)-2-(cyclohexyl)acetic acid, 4-(methoxy)benzyl ester (25 mg, 0.06 mmol, Aldehyde 6) according to the method described in Example 1, Step C to give 14 mg (38%) of the title compound. ESI-MS: 618.4 (M+H); HPLC A: 2.30 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06399619B1 |
| Source dataset | uspto-grants-2002_06 |
| ORD ID | ord-fa1687a9bba345689848288cf329e194 |
| Source note | uspto-grants-2002_06 |