HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 22458270, compound → HCID 21341087, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 22458270 | HCID 22458270 | — |
| Reactant | alpha-(R)-(3-(R)-formyl-4-(S)-phenylpyrrolidin-1-yl)-cyclohexaneacetic acid 4-methoxybenzyl ester | HCID 53654320 | — |
| Product | HCID 21341087 | HCID 21341087 | 54.4% |
Reaction Steps
The title compound was prepared from 4-(N-((3,4-difluorobenzyl)carbonyl)-N-ethylamino)piperidine trifluoroacetate (40 mg, 0.1 mmol, from Step A) and 2-(R)-(3-(R)-formyl-4-(S)-phenyl-pyrrolidin-1-yl)-2-(cyclohexyl)acetic acid, 4-(methoxy)benzyl ester (25 mg, 0.06 mmol, Aldehyde 5) according to the method described in Example 1, Step C to give 19 mg (54%) of the title compound. ESI-MS: 582.5 (M+H); HPLC A: 2.35 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06399619B1 |
| Source dataset | uspto-grants-2002_06 |
| ORD ID | ord-020154ff62ad41f28980d2fdfd517d25 |
| Source note | uspto-grants-2002_06 |