Splenotritin → HCID 11182662, compound

HRID 2185615Notes

Reaction equation

HRID 2185615 reaction equation
N[C@H:2]([C:11](NCC(NCC(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)CO)=O)CO)=O)[C@H](CC)C)=O)=O)=[O:12])[CH2:3][C:4]1[CH:9]=[CH:8][C:7](O)=C[CH:5]=1.C1[C@H]2[O:47]C(C[C@H]2[C@@H](/C=C/[C@@H](O)COC2C=C(C(F)(F)F)C=CC=2)[C@@H]1O)=O.N[C@H](C(N1CCC[C@H]1C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)CCCCN)=O)CC(C)C)=O)C)=O)CC(=O)O)=O)=O)CC1C=CC=CC=1.C(C[C@H](NC([C@@H](N)CCCN=C(N)N)=O)C(N[C@H](C(O)=O)CCC(O)=O)=O)CCN.N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N1CCC[C@H]1C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)CCCNC(=N)N)=O)CC1C=CC=CC=1)=O)CO)=O)CC1C=CC=CC=1)=O)CO)=O)=O)CC(=O)N)=O)CC(=O)O)=O)C)=O)CC(=O)N)=O)CCCCN)=O)CC1C=CC=CC=1)=O)CC1C2C(=CC=CC=2)NC=1)=O)CC(=O)O)=O)CC1C=CC=CC=1>>[CH3:7]/[CH:8]=[CH:9]/[CH:4]1[CH2:3][C@H:2]([OH:47])[C@H:11]([OH:12])[CH2:5]1

Participants

6

Reactant 5

HCID 129123SplenotritinHCID 71307583HCID 71307583, compoundHCID 131723256HCID 131723256, compoundHCID 131723257HCID 131723257, compoundHCID 131723258HCID 131723258, compound

Product 1

HCID 11182662HCID 11182662, compound

Procedure

Tyr-Gly-Gly-Ile-Ser-Ser SEQ ID NO. 8 (6 amino acids) TP-2: Phe-Pro-Asp-Ala-Leu-Lys SEQ ID NO. 9 (6 amino acids) TP-3: Phe-Asp-Trp-Phe-Lys-Asn-Ala-Asp-Asn-Pro-Ser-Phe-Ser-Phe-Arg SEQ ID NO. 10.

Sources & evidence

ORD record
ord-aa4d3d07d19644af9501b13cb575d5c2
Source dataset
uspto-grants-2002_06
Patent number
US06403362B1

Reaction notes

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