Thionyl Chloride → HCID 88192894, compound

Participants

Reaction Steps

1.2 g of 1-[2-chloro-4-fluoro-5-{3-methyl-2,6-dioxo-4-(trifluoromethyl)-1,2,3,6-tetrahydropyrimidin-1-yl}phenoxy]cyclopropanecarboxylic acid was dissolved in 12 ml of thionyl chloride and the solution was heated under reflux for 2 hours. The reaction mixture was concentrated under reduced pressure to obtain 1-[2-chloro-4-fluoro-5-{3-methyl-2,6-dioxo-4-(trifluoromethyl)-1,2,3,6-tetrahydropyrimidin-1-yl}phenoxy]cyclopropanecarboxylic acid chloride.

Provenance & Evidence