N-benzyl-3-pyrrolidinol → 3-Pyrrolidinol, 1-(phenylmethyl)-, 3-methanesulfonate, (3R)-

HRID 2185650Notes

Reaction equation

HRID 2185650 reaction equation
[CH3:1][S:2]([O:5][CH:6]1[CH2:10][CH2:9][N:8]([CH2:11][C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[CH2:7]1)(=[O:4])=[O:3].C1(CN2CCC(O)C2)C=CC=CC=1>>[CH3:1][S:2]([O:5][C@@H:6]1[CH2:10][CH2:9][N:8]([CH2:11][C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[CH2:7]1)(=[O:3])=[O:4]

Participants

3

Reactant 2

HCID 69889N-benzyl-3-pyrrolidinolHCID 98998111-Benzylpyrrolidin-3-yl methanesulfonate

Product 1

HCID 118072543-Pyrrolidinol, 1-(phenylmethyl)-, 3-methanesulfonate, (3R)-

Procedure

(rac)-3-methanesulfonyloxy-1-(phenylmethyl)-pyrrolidine, M.S. (C.I) (M/Z): 256 [M+H]+, starting from (rac)-1-(phenylmethyl)-3-pyrrolidinol.

Sources & evidence

ORD record
ord-6ff926460b1c423d9125fd83355a1946
Source dataset
uspto-grants-2002_06
Patent number
US06403573B1

Reaction notes

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