5,6,7,8-Tetrahydro-1-naphthol → (S)-3-[(2,3-dihydro-5-methoxy-1H-inden-4-yl)oxy]-1-(phenylmethyl)-pyrrolidine

HRID 2185652Notes

Reaction equation

HRID 2185652 reaction equation
[C:1]1([O:11][CH:12]2[CH2:16][CH2:15][N:14]([CH2:17][C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=3)[CH2:13]2)[C:10]2[CH2:9][CH2:8]C[CH2:6][C:5]=2[CH:4]=[CH:3][CH:2]=1.[C:24]1([OH:34])C2CCCCC=2C=CC=1>>[CH3:24][O:34][C:2]1[C:1]([O:11][C@H:12]2[CH2:16][CH2:15][N:14]([CH2:17][C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=3)[CH2:13]2)=[C:10]2[C:5](=[CH:4][CH:3]=1)[CH2:6][CH2:8][CH2:9]2

Participants

3

Reactant 2

HCID 682585,6,7,8-Tetrahydro-1-naphtholHCID 224515093-[(5,6,7,8-Tetrahydro-1-naphthalenyl)oxy]-1-(phenylmethyl)-pyrrolidine

Product 1

HCID 11759117(S)-3-[(2,3-dihydro-5-methoxy-1H-inden-4-yl)oxy]-1-(phenylmethyl)-pyrrolidine

Procedure

3-[(5,6,7,8-Tetrahydro-1-naphthalenyl)oxy]-1-(phenylmethyl)-pyrrolidine, M.S. (C.I.) (M/Z): 308 [M+H]+, starting from 5,6,7,8-tetrahydro-1-naphthol.

Sources & evidence

ORD record
ord-ac7db22e77694a6e8ae81711d4c54087
Source dataset
uspto-grants-2002_06
Patent number
US06403573B1

Reaction notes

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