HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2S)-2-(((Phenylmethoxy)carbonyl)amino)butanoic acid → 1-(n-Benzyloxycarbonyl-2(s)-aminobutyryl)-2(s)-indolinecarboxylic acid n-butylamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2S)-2-(((Phenylmethoxy)carbonyl)amino)butanoic acid | HCID 7349998 | — |
| Reactant | 2(s)-Indolinecarboxylic acid n-butylamide | HCID 11413318 | — |
| Product | 1-(n-Benzyloxycarbonyl-2(s)-aminobutyryl)-2(s)-indolinecarboxylic acid n-butylamide | HCID 11524933 | — |
Reaction Steps
The process is performed as in Example 15 c), using 0.646 g (2.73 mmol) of N-benzyloxycarbonyl-2(S)-aminobutyric acid prepared as in Example 3 a) and 0.595 g (2.73 mmol) of the amide prepared in step b). An oil is obtained which is recrystallized from CCl4.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06403561B1 |
| Source dataset | uspto-grants-2002_06 |
| ORD ID | ord-542825ccd3e84971a76bb75cebfd81be |
| Source note | uspto-grants-2002_06 |