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HRID 218571作成日:2026年10月25日

1,2,3,4-Tetrahydro-1-naphthoic acid → N-(4-isopropylphenyl)-N-[6-(tetrahydropyran-2-yloxy)hexyl]-1,2,3,4-tetrahydronaphthalene-1-carboxamide

https://huagongshe.com/reaction/218571

反応式

関与物質

役割名称HCID仕込み量
反応物1,2,3,4-Tetrahydro-1-naphthoic acidHCID 12598146—
反応物(4-Isopropylphenyl)[6-(tetrahydropyran-2-yloxy)hexyl]amineHCID 67183577—
生成物N-(4-isopropylphenyl)-N-[6-(tetrahydropyran-2-yloxy)hexyl]-1,2,3,4-tetrahydronaphthalene-1-carboxamideHCID 6841874733.5%

反応手順

By the reaction and treatment in the same manner as in Example 1 using 1,2,3,4-tetrahydronaphthalene-1-carboxylic acid (1.1 g) and (4-isopropylphenyl)[6-(tetrahydropyran-2-yloxy)hexyl]amine (2.0 g) as starting materials, N-(4-isopropylphenyl)-N-[6-(tetrahydropyran-2-yloxy)hexyl]-1,2,3,4-tetrahydronaphthalene-1-carboxamide (1.0 g) was obtained. By the reaction and treatment of this compound in the same manner as in Example 9, N-(6-hydroxyhexyl)-N-(4-isopropylphenyl)-1,2,3,4-tetrahydronaphthalene-1-carboxamide (0.64 g) was obtained.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US08198454B2
出典データセットuspto-grants-2012_06
ORD IDord-74a04fd4c42c46718a71016c75e78d51
出典メモuspto-grants-2012_06