HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Methoxy-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid → N-[(4-dimethylaminophenyl)methyl]-N-(4-isopropylphenyl)-6-methoxy-1,2,3,4-tetrahydronaphthalene-1-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Methoxy-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid | HCID 12790794 | — |
| Reactant | N-(4-(Dimethylamino)benzyl)-4-isopropylbenzenamine | HCID 21957887 | — |
| Product | N-[(4-dimethylaminophenyl)methyl]-N-(4-isopropylphenyl)-6-methoxy-1,2,3,4-tetrahydronaphthalene-1-carboxamide | HCID 59597181 | 30.2% |
Reaction Steps
By the reaction and treatment in the same manner as in Example 12 using 6-methoxy-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid (0.54 g) and [(4-dimethylaminophenyl)methyl](4-isopropylphenyl)amine (0.7 g) as starting materials, N-[(4-dimethylaminophenyl)methyl]-N-(4-isopropylphenyl)-6-methoxy-1,2,3,4-tetrahydronaphthalene-1-carboxamide (0.36 g) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08198454B2 |
| Source dataset | uspto-grants-2012_06 |
| ORD ID | ord-d76232311bf74d03a8aa101976f95c2f |
| Source note | uspto-grants-2012_06 |