3-Chloropropionitrile → HCID 15453541, compound

HRID 2185782Notes

Reaction equation

HRID 2185782 reaction equation
[CH3:1][O:2][C:3]([C:5]1[C:6](=[O:19])[NH:7][N:8]=[C:9]([C:11]2[CH:16]=[CH:15][C:14]([O:17][CH3:18])=[CH:13][CH:12]=2)[CH:10]=1)=[O:4].Cl[CH2:21][CH2:22][C:23]#[N:24]>>[C:23]([CH2:22][CH2:21][N:7]1[C:6](=[O:19])[C:5]([C:3]([O:2][CH3:1])=[O:4])=[CH:10][C:9]([C:11]2[CH:16]=[CH:15][C:14]([O:17][CH3:18])=[CH:13][CH:12]=2)=[N:8]1)#[N:24]

Participants

3

Reactant 2

HCID 109633-ChloropropionitrileHCID 15453537HCID 15453537, compound

Product 1

HCID 15453541HCID 15453541, compoundYield 78.9%

Procedure

Using 4-methoxycarbonyl-6-(4-methoxyphenyl)-2H-pyridazin-3-one and 3-chloropropionitrile as starting materials, the procedures of Example 1 were repeated likewise, whereby the title compound was obtained in a yield of 78.9%.

Sources & evidence

ORD record
ord-447a23b996cc4439a565d9a3d1c98655
Source dataset
uspto-grants-2002_06
Patent number
US06403586B1

Reaction notes

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