Bromomethylstyrene → HCID 54530989, compound

HRID 2185784Notes

Reaction equation

[Cl:1][C:2]1[CH:3]=[C:4]([C:9]2[CH:10]=[C:11]([C:16]([O:18][CH2:19][CH3:20])=[O:17])[C:12](=[O:15])[NH:13][N:14]=2)[CH:5]=[CH:6][C:7]=1[F:8].[CH2:21](Br)[CH:22]=[CH:23][C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1>>[Cl:1][C:2]1[CH:3]=[C:4]([C:9]2[CH:10]=[C:11]([C:16]([O:18][CH2:19][CH3:20])=[O:17])[C:12](=[O:15])[N:13]([CH2:21][CH:22]=[CH:23][C:24]3[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=3)[N:14]=2)[CH:5]=[CH:6][C:7]=1[F:8]

Participants

Reactant 2

HCID 98116Bromomethylstyrene

HCID 22452255HCID 22452255, compound

Product 1

HCID 54530989HCID 54530989, compoundYield 59.3%

Procedure

Using 6-(3-chloro-4-fluorophenyl)-4-ethoxycarbonyl-2H-pyridazin-3-one and cinnamyl bromide as starting materials, the procedures of Example 1 were repeated likewise, whereby the title compound was obtained in a yield of 59.3%.

Sources & evidence

ORD record: ord-2111f073ddf3417e917500553322a7b2
Source dataset: uspto-grants-2002_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06403586B1

Reaction notes

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