1-Bromo-2-methylpropane → HCID 12971765, compound
Reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([C:11]2[CH:12]=[C:13]([C:18]([O:20][CH3:21])=[O:19])[C:14](=[O:17])[NH:15][N:16]=2)[CH:6]=[CH:7][C:8]=1[O:9][CH3:10].Br[CH2:23][CH:24]([CH3:26])[CH3:25]>>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([C:11]2[CH:12]=[C:13]([C:18]([O:20][CH3:21])=[O:19])[C:14](=[O:17])[N:15]([CH2:23][CH:24]([CH3:26])[CH3:25])[N:16]=2)[CH:6]=[CH:7][C:8]=1[O:9][CH3:10]Participants
3
Procedure
Using 6-(3,4-dimethoxyphenyl)-4-methoxycarbonyl-2H-pyridazin-3-one and 1-bromo-2-methylpropane as starting materials, the procedures of Example 1 were repeated likewise, whereby the title compound was obtained in a yield of 86.6%.
Sources & evidence
- ORD record
- ord-6af3f24098ed4fcf873d497febc3af76
- Source dataset
- uspto-grants-2002_06
- Patent number
- US06403586B1
Reaction notes
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