2,4-Dichlorobenzyl chloride → 2-(2,4-Dichlorobenzyl)-4-ethoxycarbonyl-6-(4-methoxyphenyl)-2H-pyridazin-3-one

HRID 2185797Notes

Reaction equation

HRID 2185797 reaction equation
[CH2:1]([O:3][C:4]([C:6]1[C:7](=[O:20])[NH:8][N:9]=[C:10]([C:12]2[CH:17]=[CH:16][C:15]([O:18][CH3:19])=[CH:14][CH:13]=2)[CH:11]=1)=[O:5])[CH3:2].[Cl:21][C:22]1[CH:29]=[C:28]([Cl:30])[CH:27]=[CH:26][C:23]=1[CH2:24]Cl>>[Cl:21][C:22]1[CH:29]=[C:28]([Cl:30])[CH:27]=[CH:26][C:23]=1[CH2:24][N:8]1[C:7](=[O:20])[C:6]([C:4]([O:3][CH2:1][CH3:2])=[O:5])=[CH:11][C:10]([C:12]2[CH:13]=[CH:14][C:15]([O:18][CH3:19])=[CH:16][CH:17]=2)=[N:9]1

Participants

3

Reactant 2

HCID 72122,4-Dichlorobenzyl chlorideHCID 22452278HCID 22452278, compound

Product 1

HCID 129717732-(2,4-Dichlorobenzyl)-4-ethoxycarbonyl-6-(4-methoxyphenyl)-2H-pyridazin-3-oneYield 88.3%

Procedure

Using 4-ethoxycarbonyl-6-(4-methoxyphenyl)-2H-pyridazin-3-one and 2,4-dichlorobenzyl chloride as starting materials, the procedures of Example 1 were repeated likewise, whereby the title compound was obtained in a yield of 88.3%.

Sources & evidence

ORD record
ord-f8daf15161d44b34973005c0241a9665
Source dataset
uspto-grants-2002_06
Patent number
US06403586B1

Reaction notes

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