3-(Chloromethyl)pyridine hydrochloride → HCID 22452212, compound

HRID 2185800Notes

Reaction equation

HRID 2185800 reaction equation
[CH3:1][O:2][C:3]([C:5]1[C:6](=[O:19])[NH:7][N:8]=[C:9]([C:11]2[CH:16]=[CH:15][C:14]([O:17][CH3:18])=[CH:13][CH:12]=2)[CH:10]=1)=[O:4].Cl.Cl[CH2:22][C:23]1[CH:24]=[N:25][CH:26]=[CH:27][CH:28]=1>>[CH3:1][O:2][C:3]([C:5]1[C:6](=[O:19])[N:7]([CH2:22][C:23]2[CH:24]=[N:25][CH:26]=[CH:27][CH:28]=2)[N:8]=[C:9]([C:11]2[CH:16]=[CH:15][C:14]([O:17][CH3:18])=[CH:13][CH:12]=2)[CH:10]=1)=[O:4]

Participants

3

Reactant 2

HCID 233943-(Chloromethyl)pyridine hydrochlorideHCID 15453537HCID 15453537, compound

Product 1

HCID 22452212HCID 22452212, compoundYield 38.5%

Procedure

Using 4-methoxycarbonyl-6-(4-methoxyphenyl)-2H-pyridazin-3-one and 3-(chloromethyl)pyridine hydrochloride as starting materials, the procedures of Example 1 were repeated likewise, whereby the title compound was obtained in a yield of 38.5%.

Sources & evidence

ORD record
ord-7ab761fdc1d642e495898bb28967b033
Source dataset
uspto-grants-2002_06
Patent number
US06403586B1

Reaction notes

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