HCID 22452278, compound → 2-(4-Chlorocinnamyl)-4-ethoxycarbonyl-6-(4-methoxyphenyl)-2H-pyridazin-3-one

HRID 2185803Notes

Reaction equation

HRID 2185803 reaction equation
[CH2:1]([O:3][C:4]([C:6]1[C:7](=[O:20])[NH:8][N:9]=[C:10]([C:12]2[CH:17]=[CH:16][C:15]([O:18][CH3:19])=[CH:14][CH:13]=2)[CH:11]=1)=[O:5])[CH3:2].[Cl:21][C:22]1[CH:31]=[CH:30][C:25]([CH:26]=[CH:27][CH2:28]Cl)=[CH:24][CH:23]=1>>[Cl:21][C:22]1[CH:31]=[CH:30][C:25]([CH:26]=[CH:27][CH2:28][N:8]2[C:7](=[O:20])[C:6]([C:4]([O:3][CH2:1][CH3:2])=[O:5])=[CH:11][C:10]([C:12]3[CH:13]=[CH:14][C:15]([O:18][CH3:19])=[CH:16][CH:17]=3)=[N:9]2)=[CH:24][CH:23]=1

Participants

3

Reactant 2

HCID 22452278HCID 22452278, compoundHCID 53728250p-Chlorocinnamyl chloride

Product 1

HCID 537664302-(4-Chlorocinnamyl)-4-ethoxycarbonyl-6-(4-methoxyphenyl)-2H-pyridazin-3-oneYield 85.7%

Procedure

Using 4-ethoxycarbonyl-6-(4-methoxyphenyl)-2H-pyridazin-3-one and 4-chlorocinnamyl chloride as starting materials, the procedures of Example 1 were repeated likewise, whereby the title compound was obtained in a yield of 85.7%.

Sources & evidence

ORD record
ord-4dec084bec4d4d25b61db4275b6f4d0c
Source dataset
uspto-grants-2002_06
Patent number
US06403586B1

Reaction notes

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