Ethyl bromoacetate → HCID 22452281, compound

HRID 2185809Notes

Reaction equation

[CH2:1]([O:3][C:4]([C:6]1[C:7](=[O:20])[NH:8][N:9]=[C:10]([C:12]2[CH:17]=[CH:16][C:15]([O:18][CH3:19])=[CH:14][CH:13]=2)[CH:11]=1)=[O:5])[CH3:2].Br[CH2:22][C:23]([O:25][CH2:26][CH3:27])=[O:24]>>[CH2:1]([O:3][C:4]([C:6]1[C:7](=[O:20])[N:8]([CH2:22][C:23]([O:25][CH2:26][CH3:27])=[O:24])[N:9]=[C:10]([C:12]2[CH:13]=[CH:14][C:15]([O:18][CH3:19])=[CH:16][CH:17]=2)[CH:11]=1)=[O:5])[CH3:2]

Participants

Reactant 2

HCID 7748Ethyl bromoacetate

HCID 22452278HCID 22452278, compound

Product 1

HCID 22452281HCID 22452281, compoundYield 84.5%

Procedure

Using 4-ethoxycarbonyl-6-(4-methoxyphenyl)-2H-pyridazin-3-one and ethyl bromoacetate as starting materials, the procedures of Example 1 were repeated likewise, whereby the title compound was obtained in a yield of 84.5%.

Sources & evidence

ORD record: ord-6f00021f332a4da79639bf37cd968225
Source dataset: uspto-grants-2002_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06403586B1

Reaction notes

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