HuagongsheHuagongshe Chemistry Print Report · For research reference only
7-Methoxy-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid → N-[(4-chlorophenyl)methyl]-N-(4-isopropylphenyl)-7-methoxy-1,2,3,4-tetrahydronaphthalene-1-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 7-Methoxy-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid | HCID 13277484 | — |
| Reactant | N-(4-Chlorobenzyl)-4-isopropylaniline | HCID 21957952 | — |
| Product | N-[(4-chlorophenyl)methyl]-N-(4-isopropylphenyl)-7-methoxy-1,2,3,4-tetrahydronaphthalene-1-carboxamide | HCID 10204116 | 26.7% |
Reaction Steps
By the reaction and treatment in the same manner as in Example 1 using 7-methoxy-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid (1.0 g) and [(4-chlorophenyl)methyl](4-isopropylphenyl) amine (1.5 g) as starting materials, N-[(4-chlorophenyl)methyl]-N-(4-isopropylphenyl)-7-methoxy-1,2,3,4-tetrahydronaphthalene-1-carboxamide (0.58 g) was obtained. melting point: 87-88° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08198454B2 |
| Source dataset | uspto-grants-2012_06 |
| ORD ID | ord-515083d5a882456792b8f4c134e6436b |
| Source note | uspto-grants-2012_06 |